May's Anesthesia Digest

This month featured multiple practical articles on pediatric anesthesia. These articles include the use of maternal voice recordings to decrease emergence delirium, nebulized precedex in endoscopy, and a dose-finding propofol-precedex study for MRI cases.

Preoperative oral caffeine as prophylaxis against post-spinal hypotension in patients undergoing orthopedic lower limb surgery: A randomized, placebo-controlled, double-blinded study

The Takeaway

A preoperative administration of 200 mg caffeine tablet can reduce hypotensive episodes and ephedrine requirements within the first hour of spinal anesthesia

Effect of nebulized dexmedetomidine on gag reflex suppression and sedation quality in pediatric patients undergoing gastrointestinal endoscopy: a randomized controlled trial

The Takeaway

Nebulized precedex significantly decreased gag and cough reflexes, anesthetic requirements, and enhanced endoscopist satisfaction.

The effect of repeated maternal voice orientation on postoperative emergence agitation in children following tonsillectomy and adenoidectomy: A randomized controlled trial

The Takeaway

Delivering prerecorded, repeated maternal voice orientation via noise cancelling headphones decreased emergence agitation in pediatric patients undergoing tonsillectomy and adenoidectomy

Comparative efficacy of sugammadex and neostigmine in postoperative nausea and vomiting management: a meta‑analysis of randomized controlled trials

The Takeaway

In this meta-analysis, reversal with sugammadex decreased PONV metrics, especially when given at after the return of the second twitch.

Effects of Dexmedetomidine Combined With Lidocaine Topical Administration on Cough Reflex During Extubation in Thyroidectomy Patients: A Randomized Clinical Trial

The Takeaway

Topical administration of dexmedetomidine, when combined with lidocaine, significantly enhances the reduction in both the incidence and intensity of cough reflex during extubation

A dose-ranging pilot trial of dexmedetomidine-propofol in children undergoing magnetic resonance imaging

The Takeaway

An anesthetic plan with propofol infusion and single dexmedetomidine provides a safe sedation and didn't significantly extend recovery time.


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A dose-ranging pilot trial of dexmedetomidine-propofol in children undergoing magnetic resonance imaging

The Takeaway An anesthetic plan with propofol infusion and single dexmedetomidine provides a safe sedation and didn't significantly extend recovery time. Study Design * 79 children aged 1-12, scheduled for MRI * Single-center, prospective, sequential, dose-ranging trial * ASA I-III, natural airway, intravenous access prior to sedation * Propofol-Only cohort received an

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Effects of Dexmedetomidine Combined With Lidocaine Topical Administration on Cough Reflex During Extubation in Thyroidectomy Patients: A Randomized Clinical Trial

The Takeaway topical administration of dexmedetomidine, when combined with lidocaine, significantly enhances the reduction in both the incidence and intensity of cough reflex during extubation Study Design * 180 patients (60 per group) * Inclusion criteria: female patients aged 18 to 65, ASA I or II, BMI 18 to 30 kg/m²

By The Sedation Station
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